Top 10 Malware Q4 2025

MS-ISAC’s Q4 2025 Top 10 Malware report shows a 7% rise in detections, with SocGholish (30%) leading, followed by CoinMiner and Agent Tesla, and new/returning entries including ACR Stealer, Calendaromatic, SombRAT, and Arechclient2. The report outlines initial infection vectors (Multiple, Malspam, Malvertisement), and provides detailed IOCs (domains and SHA256 hashes) for each malware family—including infostealers and RATs like ACR Stealer, VenomRAT, and SombRAT—to support detection, hunting, and mitigation by SLTT defenders.