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DNA sequencers found running ancient BIOS, posing risk to clinical research

ID: 213a14f0-6cc1-5363-aa72-c57a23f0de16

STIX ID: report--213a14f0-6cc1-5363-aa72-c57a23f0de16

Feed Name: The Register (Security)

Threat Score
70/100

Date Published: 2025-01-08

Date Updated: 2026-04-26

Author: Connor Jones

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*Eclypsium researchers discovered that Illumina iSeq 100 DNA sequencers were booting an insecure 2018 BIOS/UEFI in Compatibility Support Mode without Secure Boot or firmware protections, creating risks of firmware tampering, malware/ransomware persistence, and device bricking; no active exploits were reported by Eclypsium, and Illumina has issued mitigations.*

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