The top 10 ThreatLocker policies for 2025

This document outlines ThreatLocker’s top 2024 community policies for improving endpoint security, covering Application, Network, and Event/Storage controls that detect or alert on behaviors mapped to MITRE ATT&CK (e.g., Windows event log clearing, account creation, safe mode boot, PowerShell elevation and network use, RegSvr32 outbound communications) and notable IOCs like Defender tampering; it also highlights a policy to block a revoked AnyDesk certificate tied to a prior incident, provides runner-up policies, and directs readers to the ThreatLocker Portal’s Community module for deployment and ratings.