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BIOS flaws expose iSeq DNA sequencers to bootkit attacks

ID: 30e38448-ca3f-526c-912b-def489e07c76

STIX ID: report--30e38448-ca3f-526c-912b-def489e07c76

Feed Name: Bleeping Computer

Threat Score
70/100

Date Published: 2025-01-07

Date Updated: 2026-03-27

Author: Ionut Ilascu

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Eclypsium analyzed Illumina iSeq 100 DNA sequencers and found an outdated, unprotected BIOS/UEFI (CSM mode, no Secure Boot) with multiple high- and medium-severity issues that could allow firmware overwrites, persistent implants, device bricking, or manipulation of sequencing results; Illumina was notified and issued patches, and researchers warn similar OEM motherboard designs could expose other medical/industrial devices.

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